| Assay ID | Title | Year | Journal | Article |
|---|
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID651635 | Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression | | | |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID1745845 | Primary qHTS for Inhibitors of ATXN expression | | | |
| AID504810 | Antagonists of the Thyroid Stimulating Hormone Receptor: HTS campaign | 2010 | Endocrinology, Jul, Volume: 151, Issue:7
| A small molecule inverse agonist for the human thyroid-stimulating hormone receptor. |
| AID504812 | Inverse Agonists of the Thyroid Stimulating Hormone Receptor: HTS campaign | 2010 | Endocrinology, Jul, Volume: 151, Issue:7
| A small molecule inverse agonist for the human thyroid-stimulating hormone receptor. |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID302755 | Effect on neuropathic pain in SNL rat model assessed as paw withdrawal threshold at 10 mg/kg, po | 2007 | Journal of medicinal chemistry, Nov-15, Volume: 50, Issue:23
| Discovery of orally efficacious tetracyclic metabotropic glutamate receptor 1 (mGluR1) antagonists for the treatment of chronic pain. |
| AID645617 | Antiallodynic activity in rat spinal nerve ligation model of neuropathic pain assessed as reversal of allodynia | 2012 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 22, Issue:4
| Fused tricyclic mGluR1 antagonists for the treatment of neuropathic pain. |
| AID302749 | Antagonist activity at human mGluR5b expressed in HEK293 cells assessed by measuring intracellular calcium by FLIPR assay | 2007 | Journal of medicinal chemistry, Nov-15, Volume: 50, Issue:23
| Discovery of orally efficacious tetracyclic metabotropic glutamate receptor 1 (mGluR1) antagonists for the treatment of chronic pain. |
| AID474914 | Antagonist activity at human mGluR1 | 2010 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 20, Issue:8
| A-ring modifications on the triazafluorenone core structure and their mGluR1 antagonist properties. |
| AID302756 | Inhibition of neuropathic pain in SNL rat model at 10 mg/kg, po | 2007 | Journal of medicinal chemistry, Nov-15, Volume: 50, Issue:23
| Discovery of orally efficacious tetracyclic metabotropic glutamate receptor 1 (mGluR1) antagonists for the treatment of chronic pain. |
| AID302754 | Cmax in rat at 10 mg/kg, po by CARRS | 2007 | Journal of medicinal chemistry, Nov-15, Volume: 50, Issue:23
| Discovery of orally efficacious tetracyclic metabotropic glutamate receptor 1 (mGluR1) antagonists for the treatment of chronic pain. |
| AID302751 | Displacement of [3H]9-Dimethylamino-3-(4-methoxy-phenyl)-3H-pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4-one from mGluR1 in rat cerebellum membrane | 2007 | Journal of medicinal chemistry, Nov-15, Volume: 50, Issue:23
| Discovery of orally efficacious tetracyclic metabotropic glutamate receptor 1 (mGluR1) antagonists for the treatment of chronic pain. |
| AID599764 | Antagonist activity at human mGluR5 | 2009 | Bioorganic & medicinal chemistry letters, Jun-15, Volume: 19, Issue:12
| Tricyclic thienopyridine-pyrimidones/thienopyrimidine-pyrimidones as orally efficacious mGluR1 antagonists for neuropathic pain. |
| AID599762 | Antagonist activity at human mGluR1 | 2009 | Bioorganic & medicinal chemistry letters, Jun-15, Volume: 19, Issue:12
| Tricyclic thienopyridine-pyrimidones/thienopyrimidine-pyrimidones as orally efficacious mGluR1 antagonists for neuropathic pain. |
| AID302753 | Tmax in rat at 10 mg/kg, po by CARRS | 2007 | Journal of medicinal chemistry, Nov-15, Volume: 50, Issue:23
| Discovery of orally efficacious tetracyclic metabotropic glutamate receptor 1 (mGluR1) antagonists for the treatment of chronic pain. |
| AID302748 | Antagonist activity at human mGluR1a expressed in CHO cells assessed by measuring intracellular calcium by FLIPR assay | 2007 | Journal of medicinal chemistry, Nov-15, Volume: 50, Issue:23
| Discovery of orally efficacious tetracyclic metabotropic glutamate receptor 1 (mGluR1) antagonists for the treatment of chronic pain. |
| AID302752 | AUC (0 to 6 hrs) in rat at 10 mg/kg, po by CARRS | 2007 | Journal of medicinal chemistry, Nov-15, Volume: 50, Issue:23
| Discovery of orally efficacious tetracyclic metabotropic glutamate receptor 1 (mGluR1) antagonists for the treatment of chronic pain. |
| AID599763 | Antagonist activity at rat mGluR1 | 2009 | Bioorganic & medicinal chemistry letters, Jun-15, Volume: 19, Issue:12
| Tricyclic thienopyridine-pyrimidones/thienopyrimidine-pyrimidones as orally efficacious mGluR1 antagonists for neuropathic pain. |
| AID474915 | Antagonist activity at human mGluR5 | 2010 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 20, Issue:8
| A-ring modifications on the triazafluorenone core structure and their mGluR1 antagonist properties. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |